Although it is a front-line in tuberculosis treatment, rifampicin (RF) exhibits poor oral bioavailability and hepatotoxicity.Rectal mucoadhesive and in situ rectal gels were developed to overcome drug drawbacks.A RF/polyethylene glycol 6000 co-precipitate was first prepared in different ratios.Based on the drug solubility, the selected ratio was in
ABSTRACT Influenza A viruses cause an annual contagious respiratory disease in humans and are responsible for periodic high-mortality human pandemics.Pandemic influenza A viruses usually result from the reassortment of gene segments between human and avian influenza viruses.These avian influenza virus gene segments need to adapt to humans.Here we f
In recent decades, demands for novel insecticides against mosquitoes are soaring, yet candidate chemicals with desirable properties are Hand Blown Spoons limited.Kathon is a broad-spectrum isothiazolinone microbicide, but other applications remain uncharacterized.First, we treated larvae of Culex quinquefasciatus and Aedes albopictus, two major mos
Torsional vibration of the automotive driveline has significant influence on driving comfort.This study investigates the influence of clutch nonlinear behaviors on the torsional vibration of the driveline with numerical and experimental methods.A generic automobile powertrain model with 7 degrees of freedom is proposed considering the transient eng
This paper investigates a hybrid management policy of road tolls and tradable credits in mixed road networks with both public and private roads.In the public sub-network, wnba a tradable credit scheme is applied to mitigate traffic congestion.In the private sub-network, tolls are collected by the private company, but the toll levels and toll locati